Scared and confused about lab results

Question
Hi Dr Shah,

For the past 2 yrs I have felt really fatigued, I have loss of muscle strength in my thighs and upper arms, headaches, constant thirst and increased urine output, I have night time sweating (most nights).

I have been diagnosed with Medullary Sponge Kidney(at least 10 stones in the last 11months), High Cholesterol, BP varies between 140/85-155/98 (taken numerous times) and a fast pulse rate. Most recently I am feeling dizzy and light headed.    

Blood tests - Liver Function Test= slightly raised levels

Serum Calcium= 1st test-2.85(corrected 2.73) 2nd test-2.96(corrected 2.74) 3rd test-corrected 2.62(lab range= 2.2-2.6)

24 hour urine test for Calcium was 17.9 or 714, normal for a woman is 350 in 24hrs, have been told that it is 3 times what it should be by DR and urine output was 3.5 litres (have done 3x 24hr urine test and output the same each time)

Prolactin and Glucose blood tests-

Normal Menopausal blood test-2.3 (normal)

Thyroid function-normal Diabetes blood test-normal

ParaThyroid blood test- very low at .5ng/L.

Early morning cortisol urine tests (taken over 3 days collected in 20ml sample pots)- Have been told it is low at 3 (normal is between 10-17).

I would very much appreciate it if you could help me to understand what these tests mean and possibly shed light on what is causing the symptoms.



I am really confused by the PTH serum test being so low yet the last serum calcium test is just above the accepted level and the urinery calcium excretion being very excessive and the cortisol urine spot tests being so low too.



I am under the care of an Endocrinologist at the moment but nothing seems to be getting sorted. I am so very tired, I have no energy yet I have to keep going.



I really do appreciate any comments you may have.

Thanks

Sam  


Answer
Hi Sam,



Thanks for your question on "Allexperts".



Your blood and urine calcium tests suggest that you might be suffering from hypercalciuria. That can partly explain the presence of kidney stones.



I am not an expert at interpreting the urinary cortisol levels. Please direct your question to an endocrinologist.



Sincerely,



Dr. Shah